Cedars-Sinai to build up stem cell remedies for patients with ALS Cedars-Sinai Regenerative Medicine Institute today was awarded a $17.8 million grant from the California Institute for Regenerative Medicine to build up stem cell remedies for sufferers with ALS, also known as Lou Gehrig’s Disease, a progressive, fatal and incurable neurodegenerative disease currently ensure your diagnosis . The grant – the biggest to date from the stem cell agency to Cedars-Sinai – – will fund a project with mixed stem cell and gene therapy to treat amyotrophic lateral sclerosis with stem cells found in early brain advancement and a protein called GDNF that promotes the survival of neurons.
Cautionary note about measuring perceived pain in research A cautionary note on the usage of perceived pain ratings in health outcomes researchIt is well known that pain is a highly subjective experience. We each have a pain threshold, but this can vary based on distractions and mood. A paper in the International Journal of Behavioural and Health care Research offers a cautionary take note on measuring perceived discomfort in research. There are several chronic injuries and ailments which have no well-described symptoms apart from pain, but due to the subjectivity in a patient’s reporting of their connection with the condition or injury, healthcare workers have a problem in addressing the patient’s needs. Furthermore, when subjective reporting of pain is a critical element of a scientific trial, researchers involved in the trial frequently find it hard to determine efficacy from individual to patient predicated on the subject’s personal evaluation of painful symptoms.